Ir al menú de navegación principal Ir al contenido principal Ir al pie de página del sitio

Investigación de la efectividad de varios métodos de tratamiento en cabras con papilomatosis cutánea

The Investigation of the effectiveness of various treatment methods in goats with cutaneous papillomatosis



Cómo citar
Yıldırım, Y. ., Bozkurt, G. ., Küçük, A. ., & Taşal, İbrahim. (2022). Investigación de la efectividad de varios métodos de tratamiento en cabras con papilomatosis cutánea. Revista MVZ Córdoba, 27(2), e2376. https://doi.org/10.21897/rmvz.2376

Dimensions
PlumX
Licencia
Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.

Yakup Yıldırım
Gökhan Bozkurt
Ali Küçük
İbrahim Taşal

Objetivo. Este estudio investigó los efectos de recuperación del levamisol, el extracto de Tarantula cubensis y la combinación de levamisol+extracto de T. cubensis en cabras con papilomatosis cutánea. Materiales y métodos. Se incluyeron en el estudio cuarenta cabras de pelo entre 2 y 4 años de edad en período de lactancia, que fueron diagnosticadas clínicamente de papilomatosis, y se dividieron en cuatro grupos aleatoriamente, cada uno con diez cabras. No se realizó ninguna aplicación en cabras en el grupo de control. Se administraron levamisol (5mg/kg, por vía intramuscular), extracto de T.cubensis (4ml, por vía subcutánea) y levamisol (5mg/kg, por vía intramuscular) y extracto de T.cubensis (4ml, por vía subcutánea) a las cabras en el grupo de levamisol, grupo de extracto de T. cubensis y grupo combinado, respectivamente, dos veces a intervalos semanales. Todos los animales de los grupos se controlaron a intervalos de 15 días durante tres meses. Resultados. Si bien no se observó recuperación en el grupo de control, se observó regresión en solo el papiloma de un animal (10%). Las tasas de recuperación y regresión fueron 40% y 40% en el grupo de levamisol, 30% y 40% en el grupo de extracto de T. cubensis y 60% y 30% en el grupo combinado, respectivamente. Conclusiones. Se encontró que los tres tratamientos aplicados en cabras para tratar la papilomatosis cutánea eran efectivos en diferentes grados. Cuando se comparó entre los grupos de tratamiento, se encontró que la combinación de extracto de levamisol+T. cubensis era un tratamiento más efectivo.


Visitas del artículo 542 | Visitas PDF


Descargas

Los datos de descarga todavía no están disponibles.
  1. King AMQ, Adams MJ, Carsten EB, Lefkowitz EJ. Virus taxonomy: Classification and nomenclature of viruses. Ninth Report of the International Committee on Taxonomy of Viruses, Elsevier Inc. 2012.
  2. Van Doorslaer K. Evolution of the Papillomaviridae. Virol. 2013; 445(1-2):11-20. https://doi.org/10.1016/j.virol.2013.05.012
  3. Araldi RP, Assaf SMR, De Carvalho RF, Caldas MA, De Carvalho R, De Souza JM, Magnelli RF, Modolo DG, Roperto FP, Stocco RC, Beçak W. Papillomaviruses: a systematic review. Genet Mol Biol 2017; 40:1-21. https://doi.org/10.1590/1678-4685-gmb-2016-0128
  4. Araldi RP, Melo TC, Neves AC, Spadacci-Morena DD, Magnelli RF, Modolo DG, De Sa Junior PL, Mazucchelli-de-Souza J, Carvalho RF, Beçak W, Stocca RC. Hyperproliferative action of bovine papillomavirus: genetic and histopathological aspects. Genet Mol Res. 2015; 14(4):12942-12954. https://doi.org/10.4238/2015.October.21.15
  5. Rector A, Van Ranst M. Animal papillomaviruses. Virol. 2013; 445(1-2):213-223. https://doi.org/10.1016/j.virol.2013.05.007
  6. Moulton JE. Cutaneous papillomas on the udders of milk goats. North American Veterinarian. 1954; 35:29–33.
  7. Van Doorslaer K, Rector A, Vos P, Van Ranst M. Genetic characterization of the capra hircus papillomavirus: A novel close-to-root artiodactyl papillomavirus. Virus Res. 2006; 118(1-2):164–169. https://doi.org/10.1016/j.virusres.2005.12.007
  8. Simeone P, Romanucci M, Rizzo C, Brandi R, Malatesta D, Di Guardo G, Bongiovanni L, Salda LD, Venuti A. Papillomaviruses in multiple tumours of twin goats. Open Vet. 2008; 2:33-36. https://doi.org/10.2174/1874318808002010033
  9. Dogan F, Dorttas SD, Dağalp SB, Ataseven VS, Alkan F. A teat papillomatosis case in a Damascus goat (Shami goat) in Hatay province, Turkey: a new putative papillomavirus? Arch Virol. 2018; 163(6):1635–1642. https://doi.org/10.1007/s00705-018-3781-2
  10. Lunardi M, Alfieri AA, Otonel RAA, De Alcantara BK, Rodrigues WB, De Miranda AB, and Alfieri AF. Genetic characterization of a novel bovine papillomavirus member of the Deltapapillomavirus genus. Vet Microbiol. 2013; 162(1):207–213. https://doi.org/10.1016/j.vetmic.2012.08.030
  11. Daudt C, Da Silva FRC, Lunardi M, Alves CBDT, Weber MN, Cibulski SP, Alfleri AF, Alfleri AA, Canal CW. Papillomaviruses in Ruminants: An update. Transbound Emerg Dis. 2018; 65(5):1381-1395. https://doi.org/10.1111/tbed.12868
  12. Maclachlan NJ, Dubovi EJ. Papillomaviridae and Polyomaviridae. In: Fenner’s Veterinary Virology. 5th ed, Academic Press, London. 2016. https://doi.org/10.1016/B978-0-12-800946-8.00011-8
  13. Tan MT, Yıldırım Y, Sözmen M, Dağalp SB, Yılmaz V, Kırmızıgül AH, and Gökçe E. A histopathological, immunohistochemical and molecular study of cutaneous bovine papillomatosis. Kafkas Univ Vet Fak Derg. 2012; 18:739-744. https://doi.org/ 10.9775/kvfd.2012.5341
  14. Ugochukwu ICI, Aneke CI, Idoko IS, Sani NA, Amoche AJ, Mshiela WP, Ede RE, İbrahim NDG, Njoku CIO, Sackey AKB. Bovine papilloma: aetiology, pathology, immunology, disease status, diagnosis, control, prevention and treatment: a review. Comp Clin Path. 2019; 28:737–745. https://doi.org/10.1007/s00580-018-2785-3
  15. Hamad MA, Al-Shammari AM, Odisho SM, Yaseen NY. Molecular and phylogenetic analysis of bovine papillomavirus type 1: first report in Iraqi cattle. Adv Virol. 2016; 1–7. https://doi.org/10.1155/2016/2143024
  16. Nasir L, Brandt S. Papillomavirus associated diseases of the horse. Vet Microbiol. 2013; 167(1-2):159–167. https://doi.org/10.1016/j.vetmic.2013.08.003
  17. Da Silva FRC, Daudt C, Streck AF, Weber MN, Filho RVL, Driemeier D, Canal CW. Genetic characterization of Amazonian bovine papillomavirus reveals the existence of four new putative types. Virus Gen. 2015; 51(1):77–84. https://doi.org/10.1007/s11262-015-1220-y
  18. Lunardi M, Tozato CC, Alfieri AF, De Alcantara BK, Vilas-Boas LA, Otonel RAA, Headley SA, Alfieri AA. Genetic diversity of bovine papillomavirus types, including two putative new types, in teat warts from dairy cattle herds. Arch Virol. 2016; 161(6):1569–1577. https://doi.org/10.1007/s00705-016-2820-0
  19. Roperto S, Russo V, Leonardi L, Martano M, Corrado F, Riccardi MG, Roperto F. Bovine papillomavirus type 13 expression in the urothelial bladder tumours of cattle. Transbound Emerg Dis. 2016; 63(6):628–634. https://doi.org/10.1111/tbed.12322
  20. Sharma S, Mahajan V, Gupta DK, Singh RS, Bansal BK. An epidemiological and pathological study of teat papillomas in caprines. Intas Polivet. 2015; 16:119-120. https://www.karger.com/INT
  21. Zhu W, Yuan D, Norimine J, Gao N, Fan S, Du Y, Li F, Yang M, Hu S, Dong J. Teat papillomatosis in dairy herds: First detection of bovine papillomavirus type 10 in China. J Vet Med Sci. 2019; 81(7):1063–1066. https://doi.org/10.1292/jvms.18-0449
  22. Munday JS. Bovine and human papillomaviruses: A comparative review. Vet Pathol. 2014; 51(6):1063–1075. https://doi.org/10.1177/0300985814537837
  23. Ranjan R, Ghumman SPS, Bhatt GR, Singh RS. Efficacy of autogenous vaccine and auto-hemotherapy in bovine cutaneous papillomatosis. Intas Polivet. 2013; 14:411-414. https://www.thefreelibrary.com/Efficacy+of+autogenous+vaccine+and+auto-hemotherapy+in+bovine...-a0375288607
  24. Çam Y, Kibar M, Atasever A, Atalay Ö, Beyaz L. Efficacy of levamisole and tarantula cubensis venom for the treatmentof bovine cutaneous papillomatosis. Vet Rec. 2007; 160(14):486-488. https://doi.org/10.1136/vr.160.14.486
  25. Zafar MA, Hasan M, Riaz A, Shamim A, Iqbal F, Yousaf A. Comparative therapeutic evaluation of partial excision of lesions and administering autogenous vaccine along with immune-modulators for the treatment of bovine papillomatosis. Vet Scie Res Review. 2015; 1:6-9. http://dx.doi.org/10.17582/journal.vsrr/2015.1.1.6.9
  26. Vijayasarathi MK, Shebaa A, Venkatesan M. Therapeutic management of bovine calf papillomatosis. Indian Vet. 2018; 95(09):60-61. http://ivj.org.in/users/members/viewa
  27. Kale M, Saltık HS, Hasırcıoğlu S, Yıldırım Y, Yavru S, Mamak N, Atlı K. Treatment of bovine papillomavirus-induced teat warts in a cow by using podophyllin magistral formula and autologous vaccine applications together. Indian J Anim Res. 2019; 53:832-836. https://doi.org/10.18805/ijar.B-911
  28. Renoux G. The general immunopharmocology of levamisole. Drugs. 1980; 20(2):89-99. https://doi.org/10.2165/00003495-198020020-00001
  29. Tekelioğlu BK, Parkan C, Yılmaz A, Turan N, Gürel A, Berber K, et al. Canine papillomatosis: Clinical outcome after oral isotherapy, subcutaneous tarantula cubensis venom and oral levamisole-azithromycin treatment. Bulg J Vet Med. 2017; 20(Suppl. 1):248-253. http://uni-sz.bg/truni6/wp-content/uploads/vmf/file/43%20Tekelioglu+.pdf
  30. Dhule SJ. Auto-Haemotherapy for management of caprine papillomatosis. Intas Polivet. 2013; 14(2):425-426. https://www.cabdirect.org/cabdirect/FullTextPDF/2014/20143138960.pdf
  31. İçen H, Sekin S, Simsek A, Kochan A, Tunik S. The efficacy of tarantula cubensis extract (theranekron) in treatment of canine oral papillomatosis. AJAVA. 2011; 6(7):744-749. https://scialert.net/abstract/?doi=ajava.2011.744.749
  32. Gültiken N, Vural RM. The effect of tarantula cubensis extract applied in pre and postoperative period of canine mammary tumours. JIVS. 2007; 2:13-23. https://dergipark.org.tr/tr/download/article-file/268754
  33. Paksoy Z, Gulesci N, Kandemir FM, Dinçel GD. Effectiveness of levamisole and tarantula cubensis extract in the treatment of teat papillomatosis of cows. Indian J Anim Res. 2015; 49(5):704-708. https://doi.org/10.18805/ijar.5586
  34. McDougall S, Murdough P, Pankey W, Delaney C, Barlow J, Scruton D. Relationships among somatic cell count, California mastitis test, impedance and bacteriological status of milk in goats and sheep in early lactation. Small Ruminant Res. 2001; 40(3):245–254. https://doi.org/10.1016/S0921-4488(01)00185-7

Sistema OJS 3.4.0.3 - Metabiblioteca |