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Heartland virus: a novel and emerging tick-borne encephalitis

Heartland virus: a novel and emerging tick-borne encephalitis



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Mattar V., S., & González T. M. (2016). Heartland virus: a novel and emerging tick-borne encephalitis. Revista MVZ Córdoba, 21(1), 5099-5101. https://doi.org/10.21897/rmvz.20

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Salim Mattar V.
Marco González T.

Heartland virus (HRTV) is a Bunyaviridae, phlebovirus that it has recently emerged as the causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States and China. It seems to be the HRTV has been also reported in China, Japan and Korea. Recently the first fatal case of HRTV disease in an 80-year-old Tennessee resident was reported (1)

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  1. Bosco-Lauth AM, Panella NA, Root JJ, Gidlewski T, Lash RR, Harmon JR, Burkhalter KL, Godsey MS, Savage HM, Nicholson WL, Komar N, Brault AC. Serological Investigation of Heartland Virus (Bunyaviridae: Phlebovirus) Exposure in Wild and Domestic Animals Adjacent to Human Case Sites in Missouri 2012-2013. Am J Trop Med Hyg. 2015; 92:1163-1167.
  2. Bosco-Lauth AM, Panella NA, Root JJ, Gidlewski T, Lash RR, Harmon JR, et al. Serological investigation of heartland virus (Bunyaviridae: Phlebovirus) exposure in wild and domestic animals adjacent to human case sites in Missouri 2012-2013. Am J Trop Med Hyg 2015; 92(6):1163-7. doi: 10.4269/ajtmh.14-0702.
  3. Savage HM1, Godsey MS Jr, Lambert A, Panella NA, Burkhalter KL, Harmon JR, et al. First detection of heartland virus (Bunyaviridae: Phlebovirus) from field collected arthropods. Am J Trop Med Hyg. 2013; 89(3):445-52. doi: 10.4269/ajtmh.13-0209.
  4. Xing Z, Schefers J, Schwabenlander M, Jiao Y, Liang M, Qi X, et al. Novel bunyavirus in domestic and captive farmed animals, Minnesota, USA. Emerg Infect Dis. 2013; 19(9):1487-9. doi: 10.3201/eid1909.130165.
  5. Pastula DM, Turabelidze G, Yates KF, Jones TF, Lambert AJ, Panella AJ. Notes from the field: Heartland virus disease - United States, 2012-2013. MMWR Morb Mortal Wkly Rep. 2014 Mar 28;63(12):270-1.
  6. Muehlenbachs A, Fata CR, Lambert AJ, Paddock CD, Velez JO, Blau DM. Heartland virus-associated death in Tennessee. Clin Infect Dis. 2014; 59(6):845-50. doi: 10.1093/cid/ciu434.
  7. Miranda J, Portillo A, Oteo JA, Mattar S. Rickettsia sp. Strain Colombianensi (Rickettsiales: Rickettsiaceae): A New Proposed Rickettsia Detected in Amblyomma dissimile (Acari: Ixodidae) From Iguanas and Free-Living Larvae Ticks From Vegetation. J Med Entomol 2012; 49(4):960-965. DOI: http://dx.doi.org/10.1603/ME11195.

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