Caracterización anatomopatológica de neumonías en cuyes producidas por Streptococcus pneumoniae en crianza intensiva
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Objetivo. Caracterizar macroscópica y microscópicamente las lesiones causadas por Streptococcus pneumoniae en muestras de pulmón de cuyes (Cavia porcellus) de crianza intensiva de Lima. Materiales y métodos. Se hizo la necropsia de 138 cuyes con signos clínicos de neumonía, y se tomó la muestra de los pulmones afectados. Se realizó el aislamiento bacteriano para la identificación de Streptococcus pneumoniae, utilizando agar sangre y pruebas bioquímicas; se realizó el procesamiento histopatológico utilizando la coloración hematoxilina eosina (HE) de las muestras de tejidos conservados en formol al 10%. Resultados. Del total de los pulmones diagnosticados con neumonía en necropsia, el 17.4 % (24/138) resultó positivo a Streptococcus pneumoniae; De estos, el 75% (18/24) mostró características macroscópicas de neumonía intersticial/Neumonía broncointersticial y 25% (6/24) características macroscópicas de bronconeumonía. En la evaluación microscópica se encontró que el 37.5% presentó tanto para neumonía intersticial y neumonía broncointersticial, y un 25% de ellas corresponden a bronconeumonía. Conclusión. la neumonía intersticial, neumonía broncointersticial y bronconeumonía con diagnóstico de Streptococcus pneumoniae son patrones lesionales encontradas en sistemas de crianza intensiva de Lima.
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Tamura Y. Current Approach to Rodents as Patients. Journal of Exotic Pet Medicine. 2010; 19(1):36-55. https://doi.org/10.1053/j.jepm.2010.01.014
Morales S. Patógenos oportunistas por transmisión fecal-oral en cuyes reproductores introducidos al distrito de San Marcos. Científica. 2012. 9(1):33-38. https://issuu.com/bibliotecacientifica/docs/cientifica-v9n1/37
Minarikova A, Hauptman K, Jeklova E, Knotek Z, Jekl V. Diseases in pet guinea pigs: a retrospective study in 1000 animals. VetRecord. 2015; 177(8):1-10. http://dx.doi.org/10.1136/vr.103053
Barthold SW, Griffey SM, Percy DH. Guinea Pig. Pathology of Laboratory Rodents and Rabbits. 4th. Ed. Chichester: John Wiley & Sons; 2016. http://doi.wiley.com/10.1002/9781118924051.ch05
Roberts-Steel S, Oxley JA, Carroll A, Wills AP. Frequency of Owner-Reported Bacterial Infections in Pet Guinea Pigs. Animals. 2019; 9(9):649. http://dx.doi.org/10.3390/ani9090649
Pittet LA, Hall-Stoodley L, Rutkowki MR, Harmese AG. Influenza Virus Infection Decreases Tracheal Mucociliary Velocity and Clearance of Streptococcus pneumoniae. Am J Respir Cell Mol Biol. 2010; 42(4):450-460. https://doi.org/10.1165/rcmb.2007-0417OC
Zachary, JF. Respiratory System: Mediastinum and Pleurae. In: Missouri LS, Ed. Pathologic basis of veterinary disease. 6thed. Elsevier; 2017.
Tilahun S, FekaduA, Mekibib B. Major Causes of Total Organ Condemnation and their Direct Financial Impact in Cattle Slaughtered at Hawassa Municipality Abattoir, Southern Ethiopia. J Vet Sci Technol. 2017; 8(5):1-5. https://doi.org/10.4172/2157-7579.1000473
Opzeeland YPM. Welfare issues in causes of death in young pet rabbits. [Tesis Doctoral]. Utrecht: Faculty of Veterinary Medicine Theses, Universiteit Utrecht; 2012. https://dspace.library.uu.nl/handle/1874/225791
Björklund C, Båge R, Morrell J, Kerstin de Verdier, Nisu L, Kjellinbro N et al. Diseases and causes of death among alpacas in Sweden: a retrospective study. Vet Rec. 2019; 6(1):1-7. http://dx.doi.org/10.1136/vetreco-2017-000239
Oremaiyi T, Simon U, Emmanuel A, Samson A, Sunday I, Charles E, et al. Prevalence of Gender, Age and Breed in the Occurrence of Pneumonia in Goats Slaughtered At Gwagwalada Abattoir, Abuja. IOSR-JAVS. 2019; 12(9):72-77. https://www.iosrjournals.org/iosr-javs/papers/Vol12-issue9/Series-2/L1209027277.pdf
Markey B, Leonard F, Archambault M, Cullinane A, Maguire D. Clinical Veterinary Microbiology. 2°ed. Canadá: Elsevier; 2013.
Padilla-Carlin DJ, McMurray DN, Hickey AJ. The guinea pig as a model of infectious diseases. Comp Med; 2008; 58(4):324-340. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706043/
Witkowska A, Price J, Hughes C, Smith D, White K, Alibhai A, et al. The Effects of Diet on Anatomy, Physiology and Health in the Guinea Pig. J Anim Health Behav Sci. 2017; 1(1):103. https://www.hilarispublisher.com/open-access/the-effects-of-diet-on-anatomy-physiology-and-health-in-the-guinea-pig.pdf
Gruszynski K, Young A, Levine SJ, Garvin JP, Brown S, Turner L, et al. Streptococcus equi subsp. zooepidemicus infections associated with guinea pigs. Emerg Infect Dis. 2015; 21(1):156-158. http://dx.doi.org/10.3201/eid2101.140640
Kwon YK, Lipatov AS, Swayne DE. Bronchointerstitial Pneumonia in Guinea Pigs Following Inoculation with H5N1 High Pathogenicity Avian Influenza Virus. Vet Pathol. 2009; 46(1):138-141. https://dx.doi.org/10.1354/vp.46-1-138
Hwang CK, Iuvone PM. Technical Brief: A comparison of two methods of euthanasia on retinal dopamine levels. Mol Vis . 2013; 19:1122–1124. http://www.molvis.org/molvis/v19/1122
Roustan A, Perrin J, Berthelot-Ricou A, Lopez E, Botta A, Courbiere B. Evaluating methods of mouse euthanasia on the oocyte quality: cervical dislocation versus isoflurane inhalation. LAL. 2012; 46:167–169. https://doi.org/10.1258%2Fla.2012.011115
Astaiza MJ, Benavides J, Chaves AC, Arciniegas MA, Quiroz HL. Estandarización de la técnica de necropsia en cuyes (cavia porcellus) en la Universidad de Nariño. REVIP. 2013; 2(2):77-83. http://revistas.udenar.edu.co/index.php/revip/article/view/448
Van der Linden M, Al-Lahham A, Nicklas W, Reinert, RR. Molecular Characterization of Pneumococcal Isolates from Pets and Laboratory Animals. PLoS ONE. 2009; 4(12):1-9. https://doi.org/10.1371/journal.pone.0008286
Lamm CG, Ferguson AC, Lehenbauer TW, Love BC. Streptococcal Infection in Dogs: A Retrospective Study of 393 Cases. Vet Pathol. 2010; 47(3):387-395 https://doi.org/10.1177/0300985809359601
Yarto-Jaramillo E. Respiratory System Anatomy, Physiology, and Disease: Guinea Pigs and Chinchillas. Veterinary Clinics of North America: Exotic Animal Practice. 2011; 14(2):339-355. https://doi.org/10.1016/j.cvex.2011.03.008
Rashid MM, Ferdoush MJ, Dipti M, Roy P, Rahman MM, Hossain MI, et al. Bacteriological and pathological investigation of goat lungs in Mymensingh and determination of antibiotic sensitivity. Bangl. J Vet Med. 2013; 11(2):159-166 https://doi.org/10.3329/bjvm.v11i2.19142
Caicedo-Martínez JA, Ávila-Rubiano MA, Orellano-Badillo H, Sanjuanelo-Corredor DW. Patología pulmonar en ovinos faenados del norte del departamento de Bolívar, Colombia. Ciencia & Tecnología Agropecuaria. 2017; 18(3):555-569. https://doi.org/10.21930/rcta.vol18_num3_art:744
Costa RA, Schild C, Silveira CS, Macías-Rioseco M, Mirazo S, Maya L, et al. Acute and chronic bovine pulmonary edema and emphysema in Uruguay. Pesq Veterinario Bras. 2018; 38(10):1929-1934. https://dx.doi.org/10.1590/1678-5150-pvb-5890
Cross RW, Fenton KA, Geisbert JB, Mire CE, Geisbert TW. Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig. J Infect Dis. 2015; 212(2):305-315. https://doi.org/10.1093/infdis/jiv237
Junga k, Lee CS, Kang BK, Park BK, Oh JS, Song DS. Pathology in dogs with experimental canine H3N2 influenza virus infection. Res Vet Sci. 2010; 88(3):523-527. https://doi.org/10.1016/j.rvsc.2009.11.007
Hong-Fei S, Yuan-Mao Z, Xiu-Mei D, Hong C, Lei M, Shu W, et al. Pathogenesis of a genotype C strain of bovine parainfluenza virus type 3 infection in albino guinea pigs. Virus Res. 2014; 188:1-7. https://doi.org/10.1016/j.virusres.2014.03.017
Bell TM, Bunton TE, Shaia CI, Raymond JW, Honnold SP, Donnelly GC, et al. Pathogenesis of Bolivian Hemorrhagic Fever in Guinea Pigs. Vet Pathol. 2015; 53(1):190-199. https://doi.org/10.1177/0300985815588609
Tyagita H, Bahaman AR, Jasni S, Ibrahim TAT, Fuzina NH. Pathogenicity of Leptospira icterohaemorrhagiae serovar Lai strain Langkawi in guinea pigs (Cavia porcellus). J Vet Malaysia. 2019; 31(1):1-11. http://psasir.upm.edu.my/id/eprint/70119/1/70119.pdf
Vallejo DA, Chaves CA, Morillo DP, Astaíza JM, Melo CC. Determinación histopatológica de patrones neumónicos del complejo respiratorio bovino en el municipio Pasto, Colombia. Ces Med Vet Zootec. 2016; 11(1):88-99. http://revistas.ces.edu.co/index.php/mvz/article/view/3822/2536
Betancur-Hurtado C, Castañeda-Ternera J, Gonzáles-Tous M. Inmunopatología del complejo respiratorio bovino en terneros neonatos en Montera-Colombia. Revista Científica. 2017; 27(2):95–102. https://www.redalyc.org/jatsRepo/959/95951040005/html/index.html
Yershov LA, Jordan BS, Guymon CH, Dubick MA. Relationship beteween the inoculum dose Streptococcus pneumoniae and pneumonia onset in a rabbit model. Eur Respir J. 2005; 25(4):693-700. https://doi.org/10.1183/09031936.05.00091904
Guzmán H, Mogollón JD, Rincón MA, Lora AM. Correlación entre las lesiones macroscópicas e histopatológicas de la neumonía enzoótica y la detección del Mycoplasma hyopneumoniae por PCR anidada en lavados bronco alveolares en cerdos al sacrificio. Rev Med Vet Zoot. 2008; 55(1):39-48. https://revistas.unal.edu.co/index.php/remevez/article/view/10536/14308
Song J, Wang G, Hoenerhoff MJ, Ruan J, Yang D, Zhang J, et al. Bacterial and Pneumocystis Infections in the Lungs of Gene-Knockout Rabbits with Severe Combined Immunodeficiency. Front. Immunol. 2018; 9(429):1-9. https://doi.org/10.3389/fimmu.2018.00429
Ballinger MN, Standiford TJ. Postinfluenza Bacterial Pneumonia: Host Defenses Gone Awry. JICR. 2010; 30(9):643–652. https://doi.org/10.1089/jir.2010.0049
Hick PM, Read AJ, Lugton I, Busfield F, Dawood KE, Gabor L, et al. Coronavirus infection in intensively managed cattle with respiratory disease. Aust Vet J. 2012; 90(10):381-386 https://doi.org/10.1111/j.1751-0813.2012.00978.x
Jong-Hwan P, Seung-Hyeok S, Min-Won B, Hui-Young L, Dong-Jae K, Jung-Sik C, et al. Microbiological Monitoring of Guinea Pigs Reared Conventionally at Two Breeding Facilities in Korea. Exp Anim. 2006; 55(5):427-432. https://doi.org/10.1538/expanim.55.427
Campos ALB, Silva LE, Souza T, Gabardo MP, Valério de Carvalho O, Costa M, et al. Verification of natural infection of peridomestic rodents by PCV2 on commercial swine farms. Res Vet Sci. 2013; 94(3):764–768. http://dx.doi.org/10.1016/j.rvsc.2012.10.006
Bell TM, Shaia CI, Bearss JJ, Mattix ME, Koistinen KA, Honnold S. P, et al. Temporal progression of lesions in guinea pigs infected with Lassa virus. Vet Pathol. 2017; 54(3):549-562. https://doi.org/10.1177/0300985816677153