Heartland virus: a novel and emerging tick-borne encephalitis


Salim Mattar V.
Marco González T.
Heartland virus (HRTV) is a Bunyaviridae, phlebovirus that it has recently emerged as the causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States and China. It seems to be the HRTV has been also reported in China, Japan and Korea. Recently the first fatal case of HRTV disease in an 80-year-old Tennessee resident was reported (1)
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Bosco-Lauth AM, Panella NA, Root JJ, Gidlewski T, Lash RR, Harmon JR, et al. Serological investigation of heartland virus (Bunyaviridae: Phlebovirus) exposure in wild and domestic animals adjacent to human case sites in Missouri 2012-2013. Am J Trop Med Hyg 2015; 92(6):1163-7. doi: 10.4269/ajtmh.14-0702.

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Pastula DM, Turabelidze G, Yates KF, Jones TF, Lambert AJ, Panella AJ. Notes from the field: Heartland virus disease - United States, 2012-2013. MMWR Morb Mortal Wkly Rep. 2014 Mar 28;63(12):270-1.

Muehlenbachs A, Fata CR, Lambert AJ, Paddock CD, Velez JO, Blau DM. Heartland virus-associated death in Tennessee. Clin Infect Dis. 2014; 59(6):845-50. doi: 10.1093/cid/ciu434.

Miranda J, Portillo A, Oteo JA, Mattar S. Rickettsia sp. Strain Colombianensi (Rickettsiales: Rickettsiaceae): A New Proposed Rickettsia Detected in Amblyomma dissimile (Acari: Ixodidae) From Iguanas and Free-Living Larvae Ticks From Vegetation. J Med Entomol 2012; 49(4):960-965. DOI: http://dx.doi.org/10.1603/ME11195.

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