Seguridad de la ivermectina: toxicidad y reacciones adversas en diversas especies de mamíferos

Seguridad de la ivermectina: toxicidad y reacciones adversas en diversas especies de mamíferos

Publicado 2010-05-01

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González-Canga, A., Fernández-Martínez, N., Sahagún-Prieto, A., García-Vieitez, J., Díez, M., Tamame-Martín, P., & Sierra-Vega, M. (2010). Seguridad de la ivermectina: toxicidad y reacciones adversas en diversas especies de mamíferos. Revista MVZ Córdoba, 15(2). https://doi.org/10.21897/rmvz.325
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https://doi.org/10.21897/rmvz.325
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Aránzazu González-Canga
Nélida Fernández-Martínez
Ana Sahagún-Prieto
Juan García-Vieitez
María Díez
Pedro Tamame-Martín
Matilde Sierra-Vega
Mostrar biografía de los autores

Aránzazu González-Canga

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España

Nélida Fernández-Martínez

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España

Ana Sahagún-Prieto

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España

Juan García-Vieitez

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España

María Díez

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España

Pedro Tamame-Martín

Matadero GYPISA-Talavera. Talavera de la Reina, Toledo

Matilde Sierra-Vega

Universidad de León. Departamento de Ciencias Biomédicas. Área de Farmacología. León. España
La ivermectina es un fármaco antiparasitario muy utilizado en Medicina Veterinaria, dado su espectro de actividad que abarca tanto endo como ectoparásitos, elevada eficacia y amplio margen de seguridad. No obstante, su administración puede dar lugar a efectos tóxicos. La mayoría de ellos derivan de la sobredosificación del compuesto, aunque también se han descrito, a dosis terapéuticas, casos de susceptibilidad extrema a los efectos neurotóxicos del fármaco en determinadas razas o subpoblaciones de animales, así como reacciones anafilácticas por la destrucción masiva de parásitos.

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