Hetastarch and Hetastarch + 7.2% NaCl solution in the treatment of hypovolemic diarrheic calves

Hetastarch and Hetastarch + 7.2% NaCl solution in the treatment of hypovolemic diarrheic calves

Objective. In this study, it was aimed to compare the effectiveness of Hydroxyethyl Starch (HTS), HTS +7.2% NaCl combination and Ringer Lactate solutions in the treatment of hypovolemic calves with diarrhea. Materials and methods. A total of 21 holstein calves (12 female, 9 male, weighted 28-52 kg), at the age of 0-30 days, were enrolled in the present study. The calves were randomly divided into 3 groups. Calves in the first group received HTS (10 mL / kg), calves in the second group received Hydroxyethyl starch + 7.2% NaCl combination (4 mL/kg) and calves in the third group were treated with lactated Ringer’s solution (32 mL/kg) intravenously. Calves in each group were administered with oral rehydration solution immediately, and at 8th and 16th hours after intravenous applications. Clinical examinations and laboratory findings were obtained at 0 hour, 30th minutes, 1st, 2nd, 4th, 12th and 24th hours respectively. Results. Calves in all groups achieved clinical remission with a positive response to treatment and there was no statistically significant difference in the vast majority of the variables examined, although dehydration, capillary refill time, mental status and pulse quality were better in hydroxyethyl starch group and especially in hydroxyethyl starch + 7.2% NaCl group than those of Ringer’s lactate group (p<0.05). Conclusions. In the present study, treatment of hypovolemic calves with diarrhea especially with Hydroxyethyl starch and Hydroxyethyl starch + 7.2% NaCl combination along with oral fluid therapy with the electrolyte solution was considered to be practical and effective

Objetivo. En este estudio, que tuvo como objetivo comparar la eficacia de hidroxietil almidón (HEM), HEM + 7.2% en combinación con NaCl y soluciones lactato de Ringer en el tratamiento de los terneros hipovolémicos con diarrea. Materiales y métodos. Un total de 21 terneros Holstein (12 hembras, 9 machos, con pesos entre 28-52 kg) y edad de 0-30 días, fueron consideradas en el presente estudio. Los terneros fueron divididos aleatoriamente en 3 grupos. Terneros en el primer grupo recibieron HEM (10 ml/kg), los terneros en el segundo grupo recibieron almidón + combinación hidroxietil 7.2% de NaCl (4 ml/kg) y terneros en el tercer grupo fueron tratados con solución lactato de Ringer (32 ml/kg) por vía intravenosa. A los terneros en cada grupo se les administró Rev.MVZ Córdoba 21(2):5316-5327, 2016. ISSN: 0122-0268 ORIGINAL 5317 solución de rehidratación oral inmediatamente después, y las ocho y a las 16 horas después de las aplicaciones intravenosas. Los exámenes clínicos y de laboratorio se obtuvieron a las 0 h, 30 minutos, 1, 2, 4, 12 y 24 de horas respectivamente. Resultados. Los terneros en todos los grupos alcanzaron la remisión clínica con una respuesta positiva al tratamiento y no hubo diferencia estadísticamente significativa en la mayoría de las variables examinadas; a pesar de la deshidratación, el tiempo de llenado capilar, el estado mental y la calidad de pulso fueron mejores en el grupo tratado con hidroxietil almidón y especialmente en hidroxietil almidón + 7.2% NaCl que los del grupo de lactato de Ringer (p<0.05). Conclusiones. En el presente estudio, el tratamiento de los terneros con diarrea hipovolémicos especialmente con hidroxietil almidón y almidón + 7.2% NaCl combinación hidroxietil junto con la terapia de fluido oral con la solución de electrolito fue considerado práctico y eficaz.

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