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Polimorfismos en genes candidatos a la composición de ácidos grasos y su efecto en carne Wagyu-Cross

Candidate gene polymorphism effects on the fatty acid composition of Wagyu-Cross beef



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Sánchez-Ramos, L. E. ., Sifuentes-Rincón, A. M. ., Magaña-Monforte, J. G. ., Moreno-Medina, V. R. ., & Parra-Bracamonte, G. M. (2023). Polimorfismos en genes candidatos a la composición de ácidos grasos y su efecto en carne Wagyu-Cross. Revista MVZ Córdoba, 28(2), e3090. https://doi.org/10.21897/rmvz.3090

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Luis Enrique Sánchez-Ramos
Ana María Sifuentes-Rincón
Juan Gabriel Magaña-Monforte
Victor Ricardo Moreno-Medina
Gaspar Manuel Parra-Bracamonte

Luis Enrique Sánchez-Ramos,

Instituto Politécnico Nacional. Centro de Biotecnología Genómica. Laboratorio de Biotecnología Animal. 88710, Tamaulipas, México.


Ana María Sifuentes-Rincón,

Instituto Politécnico Nacional. Centro de Biotecnología Genómica. Laboratorio de Biotecnología Animal. 88710, Tamaulipas, México.


Juan Gabriel Magaña-Monforte,

Universidad Autónoma de Yucatán. Facultad de Medicina Veterinaria y Zootecnia. 97100, Yucatán, México.


Victor Ricardo Moreno-Medina,

Instituto Politécnico Nacional. Centro de Biotecnología Genómica. Laboratorio de Biotecnología Animal. 88710, Tamaulipas, México.


Gaspar Manuel Parra-Bracamonte,

Instituto Politécnico Nacional. Centro de Biotecnología Genómica. Laboratorio de Biotecnología Animal. 88710, Tamaulipas, México.


Objetivo. Comparar la composición de ácidos grasos (FA) en la carne Wagyu y sus cruzas con Angus, Beefmaster, Brangus y Hereford, y analizar su relación con marcadores genéticos del metabolismo lipídico. Materiales y metodos. Se colectaron 111 muestras de Longissimus dorsi, las cuales se agruparon por grupo genético, se cuantificaron los FA (cromatografía de gases líquidos) y se tipificaron marcadores de ADN asociados teóricamente a FA. Se examinó el equilibrio de Hardy-Weinberg y desequilibrio de ligamiento de los marcadores y se estimó el efecto de las cruzas y el efecto de los genotipos. Resultados. Las cruzas no mostraron diferencias substanciales en la composición de FA con respecto a Wagyu. Nueve SNPs mostraron asociación con la composición de FA, y se encontró un efecto importante en el marcador SLC2A4 ss62538460, el cual influyó sobre SFA, MUFA y MUFA/SFA. Los marcadores, PLTP ss77832104 y IGF2R ss77831885 influyeron sobre C16:0, MYOZ1 ss77832104 sobre C17:1 y PPARGC1A c.1892+19 sobre C18:2. Además, se comprobaron efectos previamente descritos de MEF2C ss38329156 y SCD c.878. Conclusiones. Los presentes resultados representan una de las primeras evidencias sobre la deposición de FA en ganado Wagyu y sus cruzas y propone algunos loci en genes candidatos con posibilidad de implementación en estrategias de mejoramiento asistido.


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