Peritoneal leiomyosarcoma in a canine: case report

Leiomiosarcoma peritoneal en un canino: reporte de caso

The purpose of this study is to present a peritoneal leiomyosarcoma in a canine and its histopathological and immunohistochemical findings. The patient, a 5-year old female Chow-Chow, was brought to Los Llanos University veterinary clinic due to loss of appetite, prostration and poor corporal condition. Physical examination showed pale mucous membranes, increased abdominal silhouette with a serosanguineous fluid content. Palpation at the cranial epigastrium evidenced a painless mass of hard consistency, irregular surface and caudally displaceable. Serum biochemical abnormalities included increased plasma total protein, globulin and creatinine. Thus, an exploratory laparotomy was performed, identifying a mass in the mesentery attached to a portion of the small intestine. In its report it was stated the following macroscopic findings: a firm mass of 18 cm long and 13 cm wide, with irregular surface, great vascularization. Tissue samples were fixed in 10% buffered formalin for histopathological and immunohistochemical analysis. Samples were processed by routine methods for microscopy and stained with hematoxylin-eosin (HE), Masson trichrome, anti-cytokeratin CK5, anti-smooth muscle actin, vimentin and KIT(CD117) antibodies. In conclusion, the tumor was classified by histopathology as of mesenchymal origin and internal diffuse cytoplasmic immunopositivity of neoplastic cells for smooth muscle actin, vimentin and was negative for KIT led to diagnose of leiomyosarcoma.

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