Leishmania in skin of Rattus rattus from the urban area in the Corrientes city, Argentina

Leishmania en piel de Rattus rattus de zona urbana de la Ciudad de Corrientes, Argentina

Objective: the objective of the present work was the detection of Leishmania sp. in Rattus rattus tail base skin through polymerase chain reaction (PCR) techniques. Material and Method: We analyzed 45 Rattus rattus skin samples from the urban area of the city of Corrientes in Argentina. The Leishmania spp detection was performed by nested PCR technique. Results: Leishmania DNA was detected in 22 samples out of 45 processed (49%) in the first round of amplification, and in 14 samples (31%) in the second round (31%). Conclusions: These results contribute to increase the existing information in our region on the possible relationship between Leishmania and Rattus rattus, considering the high prevalence found in skin added to the total absence of lesions. Other aspects should be further studied to establish the role of these animals in the epidemiological chain of the disease in an urban area endemic to leishmaniasis in other animal species.

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