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Knowing and deciphering the changes or mutations that viruses undergo over time is crucial to develop epidemiological surveillance strategies for SARS CoV 2. The virus has a single-stranded RNA and has evolutionary mechanisms called mutations, which give it biological efficacy to increase its transmissibility, modify its pathogenicity, thereby evading the host’s immunity, thus modifying the antigenic response. Some time ago it was believed that changes in coronaviruses were slower than in most RNA viruses, but today relevant mutations in SARS CoV-2 have been observed today (1).
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