Perfil bioquímico hepático en cuyes alimentados con la inclusión de harina de pisonay (Erythrina edulis)

Hepatic biochemical profile in guinea pigs fed with inclusion of pisonay (Erythrina edulis) meal

Objetivo. Evaluar el efecto del porcentaje de inclusión y edad de rebrote de harina de hojas de Erythrina edulis en la respuesta de los metabolitos hepáticos de cuyes en el valle interandino de Abancay. Materiales y métodos. Se utilizó 10 cuyes machos mejorados asignados a cada dieta experimental que contenía 10, 20 y 30% de inclusión por 4, 8 y 12 meses de edad de rebrote y una dieta control con 20% de harina de alfalfa. A los 56 días se recolectaron muestras de sangre con finalidad de determinar los metabolitos hepáticos: proteína total, albumina, bilirrubina total, aminotransferasas, fosfatasa alcalina y gamma-glutamil transpeptidasa. Resultados. Los niveles séricos de la albumina, bilirrubina total, aminotransferasas y gamma-glutamil transpeptidasa fueron diferentes al grupo control (p<0.05). La proteína total y albumina (6.0 y 3.0 mg/dl) fueron mayores a los 12 meses en relación a ocho (5.8 y 2.8 mg/dl) y cuatro (5.6 y 2.8 mg/dl) meses de edad de rebrote; la bilirrubina total disminuyó hasta 0.1 mg/dl al incrementarse la edad de rebrote (p<0.05). La alanina y aspartato aminotransferasa disminuyeron por efecto de la edad de rebrote (54.0 a 34.5 UI/L; 80.7 a 56.9 UI/L, respectivamente) y el porcentaje de inclusión (46.7 a 35.8 UI/L; 75.5 a 57.7 UI/L, respectivamente) (p<0.05). La bilirrubina total disminuyó de 0.2 a 0.1 mg/dl al incrementarse el porcentaje de inclusión. Conclusiones. Los metabolitos hepáticos de cuyes mostraron variabilidad en la bilirrubina total y aminotransferasas por efecto de la inclusión y edad de rebrote de la harina de pisonay.

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